Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23206119 | 0.77 | GAA (0.35) | GAAGRM4 | |
| SCHEMBL23588699 | 0.75 | NOS3 (0.33) | GAAGRM4 | |
| SCHEMBL21196056 | 0.74 | GSK3B (0.33) | GAAGRM4 | |
| SCHEMBL22328050 | 0.71 | MAPK1 (0.33) | GAAGRM4 | |
| SCHEMBL22924137 | 0.71 | GAA (0.32) | GAAGRM4 | |
| SCHEMBL25477205 | 0.70 | GAA (0.31) | GAAGRM4 | |
| SCHEMBL19489399 | 0.69 | GAA (0.39) | GAAGRM4 | |
| SCHEMBL12866145 | 0.69 | MAP2K4 (0.51) | GAA | |
| SCHEMBL12978557 | 0.66 | ALDH1A1 (0.37) | — | |
| SCHEMBL14660332 | 0.66 | CYP1A2 (0.35) | GAAGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021129820-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | 微境生物医药科技(上海)有限公司 | 2021-07-01 | — | — | WO | disclosed |