Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22328050 | 0.85 | MAPK1 (0.33) | GAAGRM4 | |
| SCHEMBL23206119 | 0.77 | GAA (0.35) | GAAGRM4 | |
| SCHEMBL21196056 | 0.74 | GSK3B (0.33) | GAAGRM4 | |
| SCHEMBL23508726 | 0.73 | P2RX7 (0.32) | GAAGRM4NOTUMRPS6KB1 | |
| SCHEMBL19786434 | 0.72 | NOTUM (0.32) | NOTUM | |
| SCHEMBL23588699 | 0.71 | NOS3 (0.33) | GAAGRM4 | |
| SCHEMBL22924137 | 0.71 | GAA (0.32) | GAAGRM4RPS6KB1 | |
| SCHEMBL23588938 | 0.70 | GAA (0.31) | GAAGRM4 | |
| SCHEMBL19489399 | 0.69 | GAA (0.39) | GAAGRM4 | |
| SCHEMBL12866145 | 0.69 | MAP2K4 (0.51) | GAARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146829-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | UNIV TENNESSEE RES FOUND (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146829-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | AR, BRCA1, FSHR | GAA 1315/4885GRM4 1435/4885NOTUM 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.