SCHEMBL28004681

SCHEMBL28004681

CCOC(=O)C(C(=O)OC1CCCC1)(C(C)C)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.40
NAAA Q02083 2/20 0.38
CYP19A1 P11511 2/20 0.36
CYP2D6 P10635 1/20 0.35
MMP8 P22894 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
KMT2A Q03164 2/20 0.33
METAP2 P50579 1/20 0.33
MEN1 O00255 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CASP6 P55212 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28004685 0.86 RAB9A (0.36) EPHX1NAAACYP19A1ALDH1A1HTT
SCHEMBL28004677 0.84 EPHX1 (0.38) EPHX1NAAACYP19A1HTTSMN1; SMN2
SCHEMBL235893 0.80 MMP8 (0.46) MMP8ALDH1A1HTTKMT2AMEN1
SCHEMBL28004684 0.80 EPHX1 (0.42) EPHX1NAAACYP19A1CYP2D6HTT
SCHEMBL28004690 0.78 EPHX1 (0.43) EPHX1NAAACYP19A1ALDH1A1HTT
SCHEMBL28004195 0.77 EPHX1 (0.42) EPHX1NAAACYP19A1CYP2D6ALDH1A1
SCHEMBL28004242 0.74 KMT2A (0.44) EPHX1NAAACYP19A1CYP2D6ALDH1A1
SCHEMBL11991229 0.74 CYP19A1 (0.47) EPHX1NAAACYP19A1HTTSMN1; SMN2
SCHEMBL27437481 0.73 EPHX1 (0.44) EPHX1NAAACYP19A1CYP2D6ALDH1A1
SCHEMBL28014931 0.72 NAAA (0.46) EPHX1NAAACYP19A1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105837714-B The manufacturing method of solid catalyst component for olefin polymerization, the manufacturing method of polymerization of olefines catalyst and olefin polymer 东邦钛株式会社 2018-07-20 CN disclosed
CN-104640886-B The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization 东邦钛株式会社 2018-04-27 CN disclosed
CN-104470953-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2017-11-14 CN disclosed
CN-104640887-B The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization 东邦钛株式会社 2017-08-29 CN disclosed
CN-105837714-A METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER 东邦钛株式会社 2016-08-10 CN disclosed
CN-104640887-A Production method for solid catalyst component for polymerizing olefins, catalyst for polymerizing olefins, and production method for polymerized olefins TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104640886-A PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104470953-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer TOHO TITANIUM CO LTD 2015-03-25 CN disclosed