Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23589697 | 1.00 | GAA (0.42) | GAAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23589674 | 1.00 | GAA (0.42) | GAAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23589905 | 1.00 | GAA (0.42) | GAAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23589878 | 0.93 | GAA (0.43) | GAAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23589877 | 0.86 | GAA (0.52) | GAAALDH1A1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL23589693 | 0.84 | CASP2 (0.42) | GAAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16137445 | 0.83 | PTGS1 (0.38) | GAAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL24818366 | 0.77 | NAMPT (0.52) | ALDH1A1KMT2AMEN1CASP2NAMPT | |
| SCHEMBL21016062 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KMT2ASMN1; SMN2MEN1CASP2 | |
| SCHEMBL22851659 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198256-A1 | COMPOUNDS FOR THE DEGRADATION OF BRD9 OR MTH1 | C4 THERAPEUTICS, INC. (US) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198256-A1 | COMPOUNDS FOR THE DEGRADATION OF BRD9 OR MTH1 | RBBP9, MTHFD1, BRWD1 | GAA 1619/4885ALDH1A1 1439/4885KMT2A 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.