Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2758296 | 0.83 | GAA (0.57) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL14646980 | 0.81 | POLB (0.60) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL24371606 | 0.81 | GAA (0.50) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL23666032 | 0.79 | GAA (0.48) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL12190518 | 0.79 | P2RX3 (0.48) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL23771942 | 0.79 | TAS1R3 (0.39) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL29328271 | 0.78 | P2RX3 (0.44) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL15576975 | 0.78 | TUBB1 (0.50) | GAAPOLBGFERTUBB1LMNA | |
| SCHEMBL9945874 | 0.78 | LMNA (0.35) | GAAPOLBGFERALDH1A1LMNA | |
| SCHEMBL12062506 | 0.77 | POLB (0.55) | GAAPOLBGFERP2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
| WO-2021132577-A1 | ACYLSULFAMIDE COMPOUND AND PHARMACEUTICAL USE THEREFOR | 日本たばこ産業株式会社 | 2021-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | GAA 180/4885POLB 1288/4885GFER 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.