Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 2/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359326 | 0.88 | CYP3A4 (0.47) | CYP3A4CASP6CDK2ALDH1A1MEN1 | |
| SCHEMBL11416804 | 0.88 | ALDH1A1 (0.56) | CYP3A4CASP6CDK2ALDH1A1MEN1 | |
| SCHEMBL4275848 | 0.87 | ALDH1A1 (0.59) | CYP3A4CASP6CDK2ALDH1A1MEN1 | |
| SCHEMBL9827265 | 0.84 | CYP3A4 (0.59) | CYP3A4CASP6CDK2ALDH1A1MEN1 | |
| SCHEMBL9575821 | 0.82 | CASP6 (0.53) | CASP6TSHRTDP1APEX1CA1 | |
| SCHEMBL188171 | 0.80 | CYP3A4 (0.71) | CYP3A4CASP6CDK2ALDH1A1MEN1 | |
| SCHEMBL28554520 | 0.78 | CASP6 (0.47) | CYP3A4CASP6CDK2ALDH1A1MEN1 | |
| SCHEMBL16602089 | 0.77 | CA1 (0.56) | CASP6KMT2ACYP1A2TSHRTDP1 | |
| SCHEMBL9636835 | 0.77 | CYP3A4 (0.53) | CYP3A4CASP6CDK2ALDH1A1MEN1 | |
| SCHEMBL2312934 | 0.77 | POLB (0.50) | CASP6ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835677-B2 | Methods for producing aminonitrobenzoic acids | PERKINELMER HEALTH SCIENCES, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| EP-2349980-A2 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | PerkinElmer Health Sciences, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010045352-A2 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | PERKINELMER HEALTH SCIENCES, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| US-20100094046-A1 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | REVVITY HEALTH SCIENCES, INC. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094046-A1 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | AADAT, DDC, DAO | CYP3A4 432/4885CASP6 793/4885CDK2 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.