SCHEMBL23595035

SCHEMBL23595035

c1ccc(-c2cc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cc(-n3c4ccccc4c4ccc5oc6ccccc6c5c43)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPSE Q9Y251 1/20 0.31
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25133238 0.99 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10ALDH1A1NPSR1
SCHEMBL25133744 0.97 ALDH1A1 (0.33) PLA2G2APLA2G4AALDH1A1NPSR1RXFP1
SCHEMBL23595033 0.96 LMNA (0.33) PLA2G2APLA2G4APLA2G10ALDH1A1NPSR1
SCHEMBL25660283 0.96 LMNA (0.34) PLA2G2APLA2G4APLA2G10LMNASMN1; SMN2
SCHEMBL23595037 0.95 KDM4E (0.32) PLA2G2APLA2G4APLA2G10ALDH1A1NPSR1
SCHEMBL25132808 0.94 LMNA (0.34) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL25132807 0.94 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL24218000 0.94 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL18561388 0.94 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL24218106 0.92 LMNA (0.34) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230099759-A1 POLYCYCLIC COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-03-30 US disclosed
WO-2021132733-A1 POLYCYCLIC COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2021-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230099759-A1 POLYCYCLIC COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND SLCO4C1, SLCO1A2, PORCN PLA2G2A 4069/4885PLA2G4A 4733/4885PLA2G10 4568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.