Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | PGR | P06401 | 7/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829230 | 0.87 | MAOB (0.48) | MAOBPGRTP53PDK2PDK4 | |
| SCHEMBL6583223 | 0.83 | MAOB (0.61) | MAOBPGRTP53PDK2PDK4 | |
| SCHEMBL6583303 | 0.83 | MAOB (0.61) | MAOBPGRTP53PDK2PDK4 | |
| SCHEMBL6584839 | 0.82 | MAOB (0.60) | MAOBPGRTP53PDK2PDK4 | |
| SCHEMBL2270260 | 0.81 | PGR (0.70) | MAOBPGRPDK2PDK4PDE3B | |
| SCHEMBL10834864 | 0.81 | MAOB (0.55) | MAOBPGRPDK2PDK4PDE3B | |
| SCHEMBL6584678 | 0.81 | MAOB (0.58) | MAOBPGRTP53PDK2PDK4 | |
| SCHEMBL4718093 | 0.81 | MAOB (0.75) | MAOBPGRPDK2PDK4 | |
| SCHEMBL3228966 | 0.80 | HTR6 (0.45) | MAOBHSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL10834397 | 0.80 | MAOB (0.54) | MAOBPGRPDK2PDK4PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092293-A2 | CYCLOHEXYL AMIDE DERIVATIVES AS CRF RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2011-08-04 | — | — | WO | disclosed |
| US-4622336-A | ANALGESICS | SANDOZ LTD. (CH) | 1986-11-11 | — | — | US | disclosed |