Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 3/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601241 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL23601005 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTTP53 | |
| SCHEMBL23601004 | 0.84 | MAT2A (0.36) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL23601466 | 0.84 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL23601668 | 0.84 | — | — | |
| SCHEMBL23601471 | 0.83 | MAPT (0.31) | SMN1; SMN2MAPT | |
| SCHEMBL23601447 | 0.82 | — | — | |
| SCHEMBL23601584 | 0.82 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL23601010 | 0.81 | CRY1 (0.33) | SMN1; SMN2MAPTTP53 | |
| SCHEMBL23601457 | 0.81 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |