SCHEMBL23601109

SCHEMBL23601109

O=C(O)c1c(S)cccc1S

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
TSHR P16473 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ALOX15 P16050 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
ACMSD Q8TDX5 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10745781 0.85 CA12 (0.70) MAPTHDAC8CA12CA1CA2
SCHEMBL1431399 0.85 MAPT (0.64) MAPTHDAC8CA12CA1CA2
SCHEMBL31411255 0.84 ALDH1A1 (0.52) MAPTHDAC8CA12CA1CA2
SCHEMBL10415720 0.84 MAPT (0.45) MAPTHDAC8CA12CA1CA2
SCHEMBL7729674 0.84 ALDH1A1 (0.52) MAPTHDAC8CA12CA1CA2
SCHEMBL2949801 0.84 CES2 (0.54) MAPTHDAC8CA12CA1CA2
SCHEMBL2960375 0.84 L3MBTL1 (0.52) MAPTHDAC8CA12CA1CA2
SCHEMBL28462051 0.82 ALDH1A1 (0.50) MAPTHDAC8CA12CA1CA2
SCHEMBL9686142 0.80 FOLH1 (0.57) MAPTHDAC8CA12CA1CA2
SCHEMBL7823531 0.80 MAPT (0.52) MAPTHDAC8CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021131845-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD FOR FORMING PATTERN JSR株式会社 2021-07-01 WO disclosed