Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 8/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601930 | 0.79 | MAT2A (0.41) | MAT2AHRH4FNTAFNTBPRMT5 | |
| SCHEMBL23577499 | 0.73 | CSF1R (0.44) | MAT2AHRH4PRMT5CYP1A2TP53 | |
| SCHEMBL30961036 | 0.73 | CSF1R (0.44) | MAT2AHRH4PRMT5CYP1A2TP53 | |
| SCHEMBL23601772 | 0.70 | MAT2A (0.45) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL29909232 | 0.69 | HRH4 (0.43) | HRH4SMN1; SMN2HRH3TP53 | |
| SCHEMBL23577370 | 0.69 | HRH4 (0.43) | HRH4SMN1; SMN2HRH3TP53 | |
| SCHEMBL23601458 | 0.69 | MAT2A (0.36) | MAT2AHRH4FNTAFNTBPRMT5 | |
| SCHEMBL23601277 | 0.69 | MAT2A (0.36) | MAT2AHRH4FNTAFNTBPRMT5 | |
| SCHEMBL23601427 | 0.69 | MAT2A (0.36) | MAT2AHRH4FNTAFNTBPRMT5 | |
| SCHEMBL23601425 | 0.69 | MAT2A (0.36) | MAT2AHRH4FNTAFNTBPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |