Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 9/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601583 | 0.86 | FNTA (0.38) | MAT2AFNTAFNTBPRMT5CYP3A4 | |
| SCHEMBL23601772 | 0.86 | MAT2A (0.45) | MAT2AFNTAFNTBSMN1; SMN2PRMT5 | |
| SCHEMBL23601004 | 0.84 | MAT2A (0.36) | MAT2ASMN1; SMN2PRMT5HRH4MAPT | |
| SCHEMBL23601234 | 0.83 | SMN1; SMN2 (0.33) | MAT2AFNTAFNTBSMN1; SMN2PRMT5 | |
| SCHEMBL30961036 | 0.83 | CSF1R (0.44) | MAT2APRMT5HRH4MAPTCYP1A2 | |
| SCHEMBL23577499 | 0.83 | CSF1R (0.44) | MAT2APRMT5HRH4MAPTCYP1A2 | |
| SCHEMBL23577239 | 0.80 | MAT2A (0.36) | MAT2AFNTAFNTBSMN1; SMN2PRMT5 | |
| SCHEMBL29909065 | 0.80 | MAT2A (0.36) | MAT2AFNTAFNTBSMN1; SMN2PRMT5 | |
| SCHEMBL23577190 | 0.79 | MAT2A (0.37) | MAT2AFNTAFNTBSMN1; SMN2PRMT5 | |
| SCHEMBL29909135 | 0.79 | MAT2A (0.37) | MAT2AFNTAFNTBSMN1; SMN2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |