Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24806337 | 0.85 | RET (0.32) | DHODH | |
| SCHEMBL30049517 | 0.84 | ACHE (0.35) | HTR2AHTR2CHTR1AACHEBCHE | |
| SCHEMBL24813530 | 0.84 | ACHE (0.35) | HTR2AHTR2CHTR1AACHEBCHE | |
| SCHEMBL30013289 | 0.83 | TNKS (0.33) | — | |
| SCHEMBL29909439 | 0.83 | TNKS (0.33) | — | |
| SCHEMBL23576931 | 0.83 | TNKS (0.33) | — | |
| SCHEMBL23601370 | 0.82 | HTR6 (0.33) | HTR2AHTR2CHTR1AHTR6JAK2 | |
| SCHEMBL24806291 | 0.80 | PTPN11 (0.34) | HTR2AHTR2C | |
| SCHEMBL23601543 | 0.79 | ACHE (0.37) | ACHEJAK2KDM4E | |
| SCHEMBL24806334 | 0.77 | ACHE (0.31) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |