Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601547 | 0.82 | HTR2A (0.37) | HTR6HTR1AHTR2AHTR2CJAK2 | |
| SCHEMBL29909344 | 0.76 | EGFR (0.36) | HTR6HTTSMN1; SMN2 | |
| SCHEMBL23577369 | 0.76 | EGFR (0.36) | HTR6HTTSMN1; SMN2 | |
| SCHEMBL29909030 | 0.76 | KDM4E (0.33) | HTR6KDM4ELMNAMAPTHPGD | |
| SCHEMBL24807797 | 0.76 | MAP3K5 (0.31) | HTR6 | |
| SCHEMBL29909214 | 0.75 | MAPT (0.33) | HTR6PIK3CBPIK3CGMAPTSMN1; SMN2 | |
| SCHEMBL23577938 | 0.75 | MAPT (0.33) | HTR6PIK3CBPIK3CGMAPTSMN1; SMN2 | |
| SCHEMBL30049517 | 0.73 | ACHE (0.35) | HTR1AHTR2AHTR2CJAK2 | |
| SCHEMBL24813530 | 0.73 | ACHE (0.35) | HTR1AHTR2AHTR2CJAK2 | |
| SCHEMBL23576677 | 0.72 | PIK3CA (0.32) | PIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |