Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25066857 | 0.86 | KIF11 (0.51) | KDM1AIDO1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL30153536 | 0.86 | KIF11 (0.51) | KDM1AIDO1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL16906523 | 0.85 | KDM1A (0.50) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL2480559 | 0.83 | KIF11 (0.45) | KMOHSD17B1HSD17B2DHODH | |
| SCHEMBL19991635 | 0.82 | IDO1 (0.45) | IDO1METAP2HSD17B1HSD17B2NPC1 | |
| SCHEMBL11989272 | 0.82 | HPGDS (0.52) | IDO1BCHEACHEKMOHSD17B1 | |
| SCHEMBL10203003 | 0.82 | NPC1 (0.46) | KDM1AMETAP2HSD17B1HSD17B2NPC1 | |
| SCHEMBL26566412 | 0.81 | KDM1A (0.56) | KDM1AIDO1KMOCYP3A4DHODH | |
| SCHEMBL12973163 | 0.80 | HSD17B1 (0.59) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL12245311 | 0.80 | LDHA (0.47) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |