Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422110 | 0.92 | IDO1 (0.58) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL2614946 | 0.81 | KDM1A (0.50) | KDM1AIDO1HSD17B1HSD17B2KMO | |
| SCHEMBL30186373 | 0.81 | HSD17B1 (0.79) | KDM1AMETAP2HSD17B1HSD17B2 | |
| SCHEMBL22040956 | 0.81 | NPC1 (0.54) | KDM1AMETAP2HSD17B1HSD17B2RAB9A | |
| SCHEMBL29686763 | 0.81 | NPC1 (0.54) | KDM1AMETAP2HSD17B1HSD17B2RAB9A | |
| SCHEMBL16826157 | 0.81 | KDM1A (0.50) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL22053018 | 0.81 | IDO1 (0.49) | IDO1METAP2HSD17B1HSD17B2RAB9A | |
| SCHEMBL23601694 | 0.81 | KDM1A (0.50) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL2716273 | 0.79 | RAB9A (0.48) | HSD17B1HSD17B2RAB9ANPC1 | |
| SCHEMBL24636033 | 0.79 | BCHE (0.47) | KDM1AIDO1METAP2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |