Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422110 | 0.86 | IDO1 (0.58) | ACHEBCHEIDO1METAP2HSD17B1 | |
| SCHEMBL21228179 | 0.82 | HSD17B1 (0.71) | METAP2HSD17B1HSD17B2KDM1A | |
| SCHEMBL29914764 | 0.82 | HSD17B1 (0.71) | METAP2HSD17B1HSD17B2KDM1A | |
| SCHEMBL24721117 | 0.81 | IDO1 (0.48) | KDRIDO1HSD17B1HSD17B2KDM1A | |
| SCHEMBL24721383 | 0.80 | HSD17B1 (0.41) | KDRHSD17B1HSD17B2BACE1 | |
| SCHEMBL23601607 | 0.79 | KDM1A (0.53) | ACHEBCHEIDO1METAP2HSD17B1 | |
| SCHEMBL29462100 | 0.78 | FYN (0.49) | HSD17B1HSD17B2ATR | |
| SCHEMBL12498936 | 0.78 | HSD17B1 (0.67) | KDRHSD17B1HSD17B2KIT | |
| SCHEMBL21919563 | 0.77 | KDR (0.47) | KDRMETAP2HSD17B1HSD17B2KDM1A | |
| SCHEMBL16826157 | 0.76 | KDM1A (0.50) | ACHEBCHEIDO1METAP2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |