Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103844 | 0.83 | CLK4 (0.41) | ARMAP4K4WNT3AEGLN1ENPP3 | |
| SCHEMBL24721045 | 0.82 | BCL2 (0.42) | MAP4K4GRIN2B | |
| SCHEMBL24721754 | 0.81 | PTPN5 (0.46) | PTPN5MAP4K4ALDH1A1GAAATM | |
| SCHEMBL23601700 | 0.77 | L3MBTL1 (0.44) | ARALDH1A1 | |
| SCHEMBL13036072 | 0.76 | AR (0.48) | PTPN5AR | |
| SCHEMBL23600947 | 0.75 | CCR1 (0.43) | PDK2GAAHPGDRAB9AGRIN2B | |
| SCHEMBL21377212 | 0.74 | AR (0.42) | PTPN5ARPDK2MAP4K4EGLN1 | |
| SCHEMBL13680468 | 0.74 | GRIN1 (0.53) | ARMAP4K4NPC1TP53RAB9A | |
| SCHEMBL2757248 | 0.73 | MAP4K4 (0.46) | MAP4K4WNT3ARAB9AENPP3ACHE | |
| SCHEMBL4404645 | 0.73 | HSD17B1 (0.55) | MAP4K4RAB9AENPP3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |