Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680445 | 0.82 | HSD17B1 (0.46) | KDRHSD17B1HSD17B2AR | |
| SCHEMBL23601917 | 0.82 | PIK3CD (0.50) | KDRHSD17B1HSD17B2 | |
| SCHEMBL12498936 | 0.79 | HSD17B1 (0.67) | CYP1A2KDRHSD17B1HSD17B2 | |
| SCHEMBL23601702 | 0.78 | HSD17B1 (0.42) | KDRHSD17B1HSD17B2ALDH1A1AR | |
| SCHEMBL13036072 | 0.77 | AR (0.48) | AR | |
| SCHEMBL23601697 | 0.77 | PTPN5 (0.42) | ALDH1A1AR | |
| SCHEMBL2715216 | 0.76 | L3MBTL1 (0.56) | L3MBTL1CYP1A2SCN9AALDH1A1RECQL | |
| SCHEMBL8265512 | 0.76 | EGLN1 (0.51) | KDRHSD17B1HSD17B2DGAT1 | |
| SCHEMBL17157315 | 0.75 | CYP1A2 (0.53) | L3MBTL1CYP1A2SCN9AALDH1A1RECQL | |
| SCHEMBL16906666 | 0.73 | AR (0.46) | L3MBTL1ALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |