Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601692 | 0.95 | AR (0.39) | CHRNB4CHRNA3ARMAP4K4WNT3A | |
| SCHEMBL24721520 | 0.84 | RXRA (0.37) | FGFR1FGFR4FGFR3FGFR2MAP3K12 | |
| SCHEMBL18033990 | 0.78 | OPRM1 (0.38) | FGFR1FGFR4FGFR3FGFR2MAP3K12 | |
| SCHEMBL24721009 | 0.78 | RXRA (0.39) | FGFR1FGFR4 | |
| SCHEMBL876202 | 0.76 | MAP3K12 (0.50) | FGFR1FGFR4FGFR3FGFR2MAP3K12 | |
| SCHEMBL23602035 | 0.73 | OPRM1 (0.46) | ARMAP4K4 | |
| SCHEMBL23601159 | 0.72 | KDM1A (0.41) | CHRNB4CHRNA3MAP4K4WNT3A | |
| SCHEMBL12918279 | 0.72 | OPRM1 (0.40) | — | |
| SCHEMBL13805993 | 0.71 | UHRF1 (0.38) | MAP3K12 | |
| SCHEMBL13681290 | 0.71 | TNF (0.49) | ARMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |