Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601698 | 0.95 | CHRNB4 (0.38) | ARCHRNB4CHRNA3WNT3AMAP4K4 | |
| SCHEMBL24721009 | 0.83 | RXRA (0.39) | FFAR4 | |
| SCHEMBL24721520 | 0.78 | RXRA (0.37) | FFAR4MAP4K4 | |
| SCHEMBL23602035 | 0.78 | OPRM1 (0.46) | ARMAP4K4PGRENPP3 | |
| SCHEMBL12918279 | 0.77 | OPRM1 (0.40) | FFAR4NPC1RAB9AALDH1A1 | |
| SCHEMBL23601159 | 0.74 | KDM1A (0.41) | CHRNB4CHRNA3WNT3AMAP4K4PGR | |
| SCHEMBL23601688 | 0.74 | NR1H4 (0.33) | FFAR4 | |
| SCHEMBL13681290 | 0.73 | TNF (0.49) | ARMAP4K4NPC1HPGDRAB9A | |
| SCHEMBL18033990 | 0.71 | OPRM1 (0.38) | RAB9A | |
| SCHEMBL2757248 | 0.70 | MAP4K4 (0.46) | WNT3AMAP4K4RAB9AENPP3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |