SCHEMBL236025

SCHEMBL236025

CN[SiH](NC)N(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 2/20 0.35
CA12 O43570 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
FAAH O00519 1/20 0.34
PHGDH O43175 1/20 0.34
MGLL Q99685 1/20 0.34
CA1 P00915 1/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
NR3C2 P08235 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
GSK3B P49841 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3130771 0.74 MEN1 (0.46) LMNAL3MBTL1MEN1KMT2AHTT
Benzene SCHEMBL22658153 0.69 ALDH1A1 (0.56) LMNAL3MBTL1MEN1KMT2AHTT
SCHEMBL15135243 0.68 MEN1 (0.41) LMNAL3MBTL1MEN1KMT2AHTT
SCHEMBL677668 0.67 LMNA (0.46) LMNAL3MBTL1MEN1KMT2AHTT
Hydrochloric Acid SCHEMBL4552761 0.65 LMNA (0.45) LMNAL3MBTL1MEN1KMT2AHTT
SCHEMBL6865133 0.64 MEN1 (0.52) LMNAL3MBTL1MEN1KMT2AHTT
SCHEMBL21208167 0.64 ALDH1A1 (0.67) LMNAL3MBTL1MEN1KMT2AHTT
SCHEMBL16187039 0.64
SCHEMBL22931682 0.64 MEN1 (0.52) LMNAL3MBTL1MEN1KMT2AHTT
SCHEMBL7879117 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed