SCHEMBL677668

SCHEMBL677668

CNN(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 2/20 0.44
HTT P42858 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 2/20 0.39
FAAH O00519 1/20 0.38
PHGDH O43175 1/20 0.38
MGLL Q99685 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
NR3C2 P08235 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
ALDH1A1 P00352 3/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4552761 0.97 LMNA (0.45) LMNAL3MBTL1MEN1HTTKMT2A
Hydrochloric Acid SCHEMBL9080600 0.95 LMNA (0.43) LMNAL3MBTL1MEN1HTTKMT2A
SCHEMBL21075816 0.80 LTA4H (0.48) LMNAL3MBTL1MEN1HTTKMT2A
Sebacic Acid SCHEMBL28496083 0.79 HDAC6 (0.49) LMNAHTTSMN1; SMN2TSHRALDH1A1
SCHEMBL6835309 0.78 ALDH1A1 (0.61) MEN1KMT2ASMN1; SMN2TSHRCA1
SCHEMBL11651548 0.76 HTT (0.47) LMNAL3MBTL1MEN1HTTKMT2A
SCHEMBL6567263 0.76 ALDH1A1 (0.55) LMNAMEN1HTTKMT2ASMN1; SMN2
SCHEMBL4642650 0.76 HTT (0.42) LMNAL3MBTL1MEN1HTTKMT2A
SCHEMBL28125968 0.76 MEN1 (0.42) LMNAL3MBTL1MEN1HTTKMT2A
SCHEMBL609177 0.74 L3MBTL1 (0.43) LMNAL3MBTL1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185689-A Lubricating oil additive and application thereof 锦州康泰润滑油添加剂有限公司 2024-06-14 CN claimed
CN-111334129-A Preparation method of low-temperature sintered nano-silver conductive ink 善仁(浙江)新材料科技有限公司 2020-06-26 CN claimed
CN-119869473-A MOFs derived carbon-loaded sodium alginate adsorbent, preparation method and application 中国人民解放军火箭军工程大学 2025-04-25 CN disclosed
CN-222057380-U Synthesis equipment of unsymmetrical dimethylhydrazine 石家庄市冀晟化工有限责任公司 2024-11-26 CN disclosed
US-11912647-B2 Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-02-27 US disclosed
US-20210363098-A1 DIVERSITY-ORIENTED SYNTHESIS OF N,N,O-TRISUBSTITUTED HYDROXYLAMINES FROM ALCOHOLS AND AMINES BY N-O BOND FORMATION UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2021-11-25 US disclosed
EP-3802733-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2021-04-14 EP disclosed
US-20210020852-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-21 US disclosed
CN-111334129-A Preparation method of low-temperature sintered nano-silver conductive ink 善仁(浙江)新材料科技有限公司 2020-06-26 CN disclosed
US-20200087270-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2020-03-19 US disclosed
WO-2019238567-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-12-19 WO disclosed
EP-1058678-A2 METAL-CATALYZED ARYLATIONS AND VINYLATIONS OF HYDRAZINES, HYDRAZONES, HYDROXYLAMINES AND OXIMES Massachusetts Institute of Technology (US) 2000-12-13 EP disclosed
WO-1999043643-A2 METAL-CATALYZED ARYLATIONS AND VINYLATIONS OF HYDRAZINES, HYDRAZONES, HYDROXYLAMINES AND OXIMES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1999-09-02 WO disclosed
EP-0552852-B1 Polycondensed polysilazane and method of producing same TOA NENRYO KOGYO KK (JP) 1997-01-02 EP disclosed
US-5574037-A MODULATED BY SINO-ATRIAL NODE, ANTIISCHEMIC AGENT IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-11-12 US disclosed
US-5328620-A Overbased compound, metal salt of dithiophosphoric acid, ashless dispersant THE LUBRIZOL CORPORATION (US) 1994-07-12 US disclosed
EP-0552852-A2 Polycondensed polysilazane and method of producing same TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1993-07-28 EP disclosed
US-4975512-A Crosslinking with amine, ammonium, hydrazine PETROLEUM ENERGY CENTER (JP) 1990-12-04 US disclosed
EP-0304239-A1 Reformed polysilazane and method of producing same TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1989-02-22 EP disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087270-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NLRP1, NLRP3, NOD1 LMNA 1699/4885L3MBTL1 4789/4885MEN1 3390/4885
US-20210363098-A1 DIVERSITY-ORIENTED SYNTHESIS OF N,N,O-TRISUBSTITUTED HYDROXYLAMINES FROM ALCOHOLS AND AMINES BY N-O BOND FORMATION ADH5, ADH1A, NAT1 LMNA 3209/4885L3MBTL1 2634/4885MEN1 3283/4885
US-11912647-B2 Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation ADH5, ADH1A, NAT1 LMNA 3243/4885L3MBTL1 2657/4885MEN1 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.