SCHEMBL2360435

SCHEMBL2360435

BrC(Br)=C(Br)c1cccc(Br)c1Br

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.32
GAA P10253 1/20 0.32
MAOB P27338 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40038 0.80 NPC1 (0.39) MEN1KMT2A
SCHEMBL29927048 0.80 NPC1 (0.39) MEN1KMT2A
SCHEMBL4758788 0.80 MAOB (0.36) PRNPGAAMAOBMEN1KMT2A
SCHEMBL526549 0.77 PRNP (0.39) PRNPMAOBMEN1KMT2A
SCHEMBL16960567 0.73 ALDH1A1 (0.35) PRNPGAAMAOBMEN1KMT2A
SCHEMBL8495468 0.73 PRNP (0.50) PRNPGAAMAOBMEN1KMT2A
SCHEMBL588389 0.71 PRNP (0.53) PRNPKMT2A
SCHEMBL30285353 0.71 MEN1 (0.40) PRNPGAAMEN1KMT2A
SCHEMBL3170417 0.70 METAP2 (0.48) GAA
SCHEMBL28482995 0.70 PRNP (0.39) PRNPGAAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563304-B Flame-retardant polyester composition 爱思乐-艾博美国有限公司 2021-07-20 CN claimed
US-4394484-A Polypentabromostyrene, process for the production and use CHEMISCHE FABRIK KALK GMBH (DE) 1983-07-19 US claimed
JP-5009227-A None JP disclosed
CN-109563304-B Flame-retardant polyester composition 爱思乐-艾博美国有限公司 2021-07-20 CN disclosed
CN-112679948-A Flame-retardant reinforced semi-aromatic polyamide molding composition with specific glass fiber length and molded product 金发科技股份有限公司 2021-04-20 CN disclosed
WO-2015172673-A1 NUCLEATION COMPOSITIONS FOR POLYESTER COMPOSITE, FLAME RETARDANT POLYESTER COMPOSITE MOLDING COMPOSITIONS FOR INJECTION MOLDING AND PREPARATION THEREOF HONEYWELL INTERNATIONAL INC. (US) 2015-11-19 WO disclosed
EP-1572806-B1 PROCESS FOR PREPARING A FLAME RETARDANT POLYAMIDE COMPOSITION DSM IP ASSETS BV (NL) 2012-08-08 EP disclosed
EP-1712593-B1 FLAME-RETARDANT POLYAMIDE COMPOSITION AND USE THEREOF MITSUI CHEMICALS INC (JP) 2011-08-10 EP disclosed
US-7572856-B2 high temperature engineering polytetetraethylene adipamide ; containing melamine pyrophosphate and/or brominated polystyrene and antimony trioxide as fire retardant; free of polyamide oligomer with a molecular weight of 5000 or less with 5-30 carbons as the terminals, polyhexamethylene adipamide 100% DSM IP ASSETS B.V. (NL) 2009-08-11 US disclosed
EP-1273628-B1 MOLDING MATERIAL FOR ELECTRICAL AND ELECTRONIC PARTS MITSUI CHEMICALS INC (JP) 2009-01-07 EP disclosed
US-7452934-B2 Flame retardant polyamide composition DSM IP ASSETS B.V. (NL) 2008-11-18 US disclosed
US-4546126-A POLYBUTYLENE TEREPHTHALATE ORT POLYBUTYLENE TEREPHTHALTE - POLYETHYLENE TEREPHTHALATE COPOLYMERS CIBA GEIGY CORPORATION (US) 1985-10-08 US disclosed
US-4521560-A STIFFNESS, TRACKING RESISTANCE CIBA GEIGY CORPORATION (US) 1985-06-04 US disclosed
US-4499219-A CONTAINING AN EXPXIDE AND BISOXAZOLINE, DIIMIDE OR TRIACYLAMINE;HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1985-02-12 US disclosed
US-4456723-A POLYESTER WITH ANHYDROUS CALCIUM PHOSPHATE CIBA-GEIGY CORPORATION (US) 1984-06-26 US disclosed
US-4401784-A ADDING DOLOMITE TO INCREASE STIFFNESS AND DIMENSIONAL STABILITY UNDER HEAT CIBA-GEIGY CORPORATION (US) 1983-08-30 US disclosed
US-4394484-A Polypentabromostyrene, process for the production and use CHEMISCHE FABRIK KALK GMBH (DE) 1983-07-19 US disclosed
US-4394484-A Polypentabromostyrene, process for the production and use CHEMISCHE FABRIK KALK GMBH (DE) 1983-07-19 US disclosed
US-4373044-A REDUCING CORROSIVE ACTION ON METALS OR ALLOYS BY INCLUDING AEROSOL OF AN OXIDE CIBA-GEIGY CORPORATION (US) 1983-02-08 US disclosed
EP-0043906-A2 Process for the preparation of penta-bromostyrene polymers and their use Chemische Fabrik Kalk GmbH (DE) 1982-01-20 EP disclosed