SCHEMBL4758788

SCHEMBL4758788

Br[C](Br)c1cccc(Br)c1Br

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.36
GAA P10253 1/20 0.34
PRNP P04156 1/20 0.34
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 3/20 0.31
FABP4 P15090 1/20 0.31
CTSL P07711 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2360435 0.80 PRNP (0.32) MAOBGAAPRNPMEN1KMT2A
SCHEMBL153460 0.78 NPC1 (0.42) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL8495468 0.77 PRNP (0.50) MAOBGAAPRNPMEN1KMT2A
SCHEMBL16960567 0.77 ALDH1A1 (0.35) MAOBGAAPRNPMEN1KMT2A
SCHEMBL156339 0.76 ERN1 (0.32)
SCHEMBL588389 0.75 PRNP (0.53) PRNPKMT2AALDH1A1FABP4HPGD
SCHEMBL28482995 0.73 PRNP (0.39) MAOBGAAPRNPMEN1KMT2A
SCHEMBL3170417 0.73 METAP2 (0.48) GAAALDH1A1HPGDHSD17B10
SCHEMBL9136350 0.73 PRNP (0.56) MAOBGAAPRNPMEN1KMT2A
SCHEMBL28958191 0.73 ALDH1A1 (0.37) GAAPRNPMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP claimed
CN-114651049-A Photocurable compositions containing high refractive index monomers for 3D printing applications 阿科玛法国公司 2022-06-21 CN claimed
WO-2021048628-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2021-03-18 WO claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US disclosed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP disclosed
CN-114651049-A Photocurable compositions containing high refractive index monomers for 3D printing applications 阿科玛法国公司 2022-06-21 CN disclosed
WO-2021048628-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2021-03-18 WO disclosed
EP-2944673-A1 POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION, AND MOLDED ARTICLE Mitsubishi Engineering-Plastics Corporation (JP) 2015-11-18 EP disclosed
WO-2008073534-A1 METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-06-19 WO disclosed
US-7341784-B2 Light management film and its preparation and use GENERAL ELECTRIC COMPANY (US) 2008-03-11 US disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
EP-1631603-A1 CURABLE (METH)ACRYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-03-08 EP disclosed
EP-1512704-A1 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2005-03-09 EP disclosed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed
US-6833391-B1 Comprising three monomers having highly brominated phenyl, arylether and bisphenol A or F functionality and initiator; light management films; high refractive index; brightness GENERAL ELECTRIC COMPANY 2004-12-21 US disclosed
WO-2004106396-A1 CURABLE (METH)ACRYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2004-12-09 WO disclosed
US-20040249100-A1 CURABLE (METH)ACRYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2004-12-09 US disclosed
US-20040242720-A1 Curable (meth)acrylate compositions CITIBANK, N.A., AS COLLATERAL AGENT 2004-12-02 US disclosed
US-4301088-A Method of preparing benzyl alcohols by decarbonylation of formic acid esters DYNAMIT NOBEL AG (DE) 1981-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom MACF1, WASF2, THEM6 MAOB 4170/4885GAA 3042/4885PRNP 1417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.