SCHEMBL23606151

SCHEMBL23606151

Clc1ccc2[nH]c3cccc(Br)c3c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 1/20 0.42
CCNB2 O95067 1/20 0.42
CCNE2 O96020 1/20 0.42
CDK1 P06493 1/20 0.42
CDK4 P11802 1/20 0.42
CCNB1 P14635 1/20 0.42
PRKACA P17612 1/20 0.42
PRKACG P22612 1/20 0.42
PRKACB P22694 1/20 0.42
CCND1 P24385 1/20 0.42
CCNE1 P24864 1/20 0.42
CDK2 P24941 1/20 0.42
CAMK2B Q13554 1/20 0.42
CAMK2G Q13555 1/20 0.42
CAMK2D Q13557 1/20 0.42
CCNB3 Q8WWL7 1/20 0.42
CAMK2A Q9UQM7 1/20 0.42
HTR2A P28223 2/20 0.42
HTR2C P28335 2/20 0.42
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28474458 0.82 GABRP (0.50) CHUKCCNB2CCNE2CDK1CDK4
SCHEMBL29530429 0.82 GABRP (0.50) CHUKCCNB2CCNE2CDK1CDK4
SCHEMBL7252325 0.81 PARP1 (0.49) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL25565271 0.77 CHUK (0.50) CHUKLMNAMEN1KMT2ARXFP1
SCHEMBL29724222 0.77 IMPDH2 (0.59) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL420335 0.77 IMPDH2 (0.59) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL30033706 0.77 MEN1 (0.42) CHUKCCNB2CCNE2CDK1CDK4
SCHEMBL17001234 0.77 CDK4 (0.55) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL27146906 0.77 MEN1 (0.42) CHUKCCNB2CCNE2CDK1CDK4
SCHEMBL23702733 0.76 AR (0.49) CHUKCCNE2CDK4CCND1CCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021128764-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-01 WO disclosed