SCHEMBL25565271

SCHEMBL25565271

Clc1ccc2[nH]c3ccc4c(ccc5[nH]c6ccc(Cl)cc6c54)c3c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 1/20 0.50
LMNA P02545 1/20 0.48
CDC25A P30304 1/20 0.47
CDC25C P30307 1/20 0.47
HPGD P15428 2/20 0.47
CYP1A2 P05177 1/20 0.47
GAA P10253 1/20 0.47
PARP1 P09874 1/20 0.46
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
PTGS2 P35354 2/20 0.44
ABCC4 O15439 1/20 0.44
C5 P01031 1/20 0.44
MAPT P10636 1/20 0.44
PTGS1 P23219 1/20 0.44
PDE4D Q08499 1/20 0.44
RXFP1 Q9HBX9 1/20 0.43
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20208814 0.87 PARP1 (0.50) CHUKLMNACDC25ACDC25CHPGD
SCHEMBL29371976 0.87 PARP1 (0.50) CHUKLMNACDC25ACDC25CHPGD
SCHEMBL607827 0.84 CHUK (0.64) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL29453525 0.84 CHUK (0.64) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL30512157 0.81 CDK4 (0.53) CHUKLMNAMEN1KMT2ARXFP1
SCHEMBL22155551 0.81 CDK4 (0.53) CHUKLMNAMEN1KMT2ARXFP1
SCHEMBL550449 0.79 CHUK (0.60) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL30033706 0.79 MEN1 (0.42) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL24032468 0.77 CDK4 (0.66) CHUKPARP1MEN1KMT2ARXFP1
SCHEMBL23606151 0.77 CHUK (0.42) CHUKLMNAHPGDCYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230140877-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-05-11 US disclosed
US-20230140749-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-05-04 US disclosed
US-20230140749-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140749-A1 Novel Compound and Organic Light Emitting Device Comprising the Same ARL1, LAS1L, AR CHUK 2927/4885LMNA 1067/4885CDC25A 3665/4885
US-20230140877-A1 Novel Compound and Organic Light Emitting Device Comprising the Same CRY2, CRY1, GLI1 CHUK 2342/4885LMNA 4222/4885CDC25A 2955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.