SCHEMBL2360751

SCHEMBL2360751

C=CCN(C=Cc1ccc(N)cc1)CC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.38
CYP19A1 P11511 12/20 0.38
NQO2 P16083 2/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
PSMD14 O00487 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
RECQL P46063 1/20 0.36
GFER P55789 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.32
KCNH2 Q12809 1/20 0.32
PRKCI P41743 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015207 0.74 ALDH1A1 (0.46) ALDH1A1TSHRTDP1L3MBTL1KCNH2
SCHEMBL6015206 0.74 ALDH1A1 (0.46) ALDH1A1TSHRTDP1L3MBTL1KCNH2
SCHEMBL473073 0.71 ALDH1A1 (0.44) CYP19A1MAOAMAOBALDH1A1TSHR
SCHEMBL6742362 0.71 ALDH1A1 (0.44) CYP19A1MAOAMAOBALDH1A1TSHR
SCHEMBL8204834 0.68 ALDH1A1 (0.67) PSMD14ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL10834525 0.67 NFE2L2 (0.48) APPNQO2MAOAMAOB
SCHEMBL11171879 0.66 NPC1 (0.48) MAOBTDP1L3MBTL1
SCHEMBL9250076 0.66 APP (0.50) APPCYP19A1NQO2MAOAMAOB
SCHEMBL136178 0.66 NPC1 (0.48) MAOBTDP1L3MBTL1
SCHEMBL9250081 0.66 APP (0.50) APPCYP19A1NQO2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014043267-A1 METHODS OF FABRICATING PHOTOACTIVE SUBSTRATES SUITABLE FOR ELECTROMAGNETIC TRANSMISSION AND FILTERING APPLICATIONS LIFE BIOSCIENCE, INC. (US) 2014-03-20 WO disclosed
WO-2011100445-A1 METHODS TO FABRICATE A PHOTOACTIVE SUBSTRATE SUITABLE FOR MICROFABRICATION LIFE BIOSCIENCE, INC. (US) 2011-08-18 WO disclosed
WO-2010011939-A2 ASSAY PLATES, METHODS AND SYSTEMS HAVING ONE OR MORE ETCHED FEATURES LIFE BIOSCIENCE, INC. (US) 2010-01-28 WO disclosed