Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015207 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TAS1R3TAS1R1CHRNB4CHRNA3 | |
| SCHEMBL10834525 | 0.79 | NFE2L2 (0.48) | — | |
| SCHEMBL11171879 | 0.78 | NPC1 (0.48) | TDP1NPC1L3MBTL1 | |
| SCHEMBL136178 | 0.78 | NPC1 (0.48) | TDP1NPC1L3MBTL1 | |
| SCHEMBL27707174 | 0.78 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL6015208 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CHRNB4CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL6015209 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CHRNB4CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL2360751 | 0.74 | APP (0.38) | ALDH1A1TSHRTDP1L3MBTL1KCNH2 | |
| SCHEMBL9915854 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TSHRMEN1LMNAMAPT | |
| Butane SCHEMBL28268770 | 0.71 | ALDH1A1 (0.69) | ALDH1A1TAS1R3TAS1R1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091274-B2 | A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1318172-B1 | Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black | GOODYEAR TIRE & RUBBER (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-0924227-B1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-20030125448-A1 | A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-07-03 | — | — | US | disclosed |
| EP-1318172-A1 | Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6191234-B1 | CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD | JSR CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0924227-A1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR Corporation (JP) | 1999-06-23 | — | — | EP | disclosed |