Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F11 | P03951 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25366796 | 0.83 | LMNA (0.38) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL23607748 | 0.81 | LIPG (0.49) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL30413431 | 0.74 | CA1 (0.43) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL16396475 | 0.74 | CA1 (0.43) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL1283942 | 0.74 | DGAT1 (0.44) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL15000479 | 0.74 | LIPG (0.45) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL25284945 | 0.74 | F11 (0.40) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL30464597 | 0.74 | F11 (0.40) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL1362550 | 0.73 | MEN1 (0.42) | LMNATSHRMEN1KMT2AHTT | |
| SCHEMBL18497287 | 0.73 | AAK1 (0.40) | F2F11PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |