Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.37 |
| ▸ | LPL | P06858 | 4/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | F11 | P03951 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17289557 | 0.85 | F11 (0.42) | LIPGLPLP4HBF2F11 | |
| SCHEMBL17289554 | 0.85 | F11 (0.42) | LIPGLPLP4HBF2F11 | |
| SCHEMBL27179471 | 0.81 | LIPG (0.42) | LIPGLPLP4HBF2F11 | |
| SCHEMBL27179468 | 0.81 | LIPG (0.42) | LIPGLPLP4HBF2F11 | |
| SCHEMBL4985164 | 0.79 | ROCK1 (0.42) | LIPGLPLP4HBF2F11 | |
| SCHEMBL1658478 | 0.78 | PTGS1 (0.48) | LIPGLPLP4HBHIF1A | |
| SCHEMBL16468540 | 0.78 | AAK1 (0.38) | LIPGLPLROCK1AAK1HIF1A | |
| SCHEMBL15609345 | 0.76 | ALDH1A1 (0.43) | ALOX5 | |
| SCHEMBL24387204 | 0.75 | AAK1 (0.41) | LIPGLPLROCK1AAK1HIF1A | |
| SCHEMBL5206385 | 0.74 | HIF1A (0.46) | HIF1AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |