SCHEMBL2360799

SCHEMBL2360799

CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)OC(=O)CCCCCNc1ccc([N+](=O)[O-])c2nonc12

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ S1PR1 P21453 4/20 0.53
▸ S1PR3 Q99500 3/20 0.53
▸ S1PR4 O95977 2/20 0.53
▸ S1PR5 Q9H228 2/20 0.53
▸ SELP P16109 1/20 0.50
▸ NR5A2 O00482 1/20 0.45
▸ NR5A1 Q13285 1/20 0.45
▸ FABP3 P05413 1/20 0.43
▸ GSTM2 P28161 1/20 0.43
▸ LPAR1 Q92633 1/20 0.41
▸ LPAR3 Q9UBY5 1/20 0.41
▸ ENPP2 Q13822 1/20 0.41
▸ P2RY10 O00398 4/20 0.40
▸ GPR34 Q9UPC5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6704299 0.96 S1PR1 (0.48) S1PR1S1PR3S1PR4S1PR5SELP
SCHEMBL6510371 0.96 S1PR1 (0.48) S1PR1S1PR3S1PR4S1PR5SELP
SCHEMBL4222844 0.90 FABP3 (0.50) S1PR1S1PR3S1PR4S1PR5SELP
SCHEMBL4419953 0.90 S1PR1 (0.47) S1PR1S1PR3S1PR4S1PR5SELP
SCHEMBL2622729 0.89 SELP (0.53) S1PR1S1PR3S1PR4S1PR5SELP
SCHEMBL12272715 0.87 S1PR1 (0.56) S1PR1S1PR3S1PR4S1PR5GSTM2
SCHEMBL15500035 0.87 S1PR1 (0.56) S1PR1S1PR3S1PR4S1PR5GSTM2
SCHEMBL17240248 0.87 S1PR1 (0.56) S1PR1S1PR3S1PR4S1PR5GSTM2
SCHEMBL3424607 0.86 PRKCA (0.55) S1PR1S1PR3S1PR4S1PR5SELP
SCHEMBL4407962 0.86 SMN1; SMN2 (0.56) S1PR1S1PR3S1PR4S1PR5SELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692999-B2 Method of screening ATP11C or CDC50A inhibitor KYOTO UNIVERSITY (JP) 2023-07-04 — — US disclosed
US-20230066723-A1 MICROPARTICLE COMPOSITIONS YEH JAMES SHUE MIN (GB) 2023-03-02 — — US disclosed
US-20210311019-A1 METHOD OF SCREENING ATP11C OR CDC50A INHIBITOR KYOTO UNIVERSITY (JP) 2021-10-07 — — US disclosed
US-11073510-B2 Method of screening ATP11C or CDC50A inhibitor KYOTO UNIVERSITY (JP) 2021-07-27 — — US disclosed
EP-2934599-B1 MICROPARTICLE COMPOSITIONS YEH JAMES SHUE MIN (GB) 2020-05-27 — — EP disclosed
EP-2890365-B1 NANOPARTICLE FORMULATION RES & INNOVATION UK (GB) 2019-11-20 — — EP disclosed
US-20190242873-A1 METHOD OF SCREENING ATP11C OR CDC50A INHIBITOR KYOTO UNIVERSITY (JP) 2019-08-08 — — US disclosed
EP-3130924-B1 METHOD FOR SCREENING FOR INHIBITOR OF ATP11C OR CDC50A UNIV KYOTO (JP) 2019-06-12 — — EP disclosed
US-10201499-B2 Nanoparticle formulation UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2019-02-12 — — US disclosed
EP-3130924-A1 METHOD FOR SCREENING FOR INHIBITOR OF ATP11C OR CDC50A Kyoto University (JP) 2017-02-15 — — EP disclosed
EP-2934599-A1 MICROPARTICLE COMPOSITIONS Yeh, James Shue-Min (GB) 2015-10-28 — — EP disclosed
US-20150224054-A1 NANOPARTICLE FORMULATION IMPERIAL INNOVATIONS LTD (GB) 2015-08-13 — — US disclosed
EP-2890365-A1 NANOPARTICLE FORMULATION Medical Research Council (GB) 2015-07-08 — — EP disclosed
WO-2014096859-A1 MICROPARTICLE COMPOSITIONS YEH JAMES SHUE-MIN (GB) 2014-06-26 — — WO disclosed
WO-2014033453-A1 NANOPARTICLE FORMULATION MEDICAL RESEARCH COUNCIL (GB) 2014-03-06 — — WO disclosed
WO-2011098578-A2 LIPOSOME SYSTEM FOR OCULAR ADMINISTRATION BIONEER A/S (DK) 2011-08-18 — — WO disclosed
US-7132122-B2 Direct micro-patterning of lipid bilayers using UV light and selected uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-11-07 — — US disclosed
WO-2006104639-A2 DEVICE COMPRISING ARRAY OF MICRO-OR NANO-RESERVOIRS STANFORD UNIVERSITY (US) 2006-10-05 — — WO disclosed
WO-2004111185-A2 DIRECT MICRO-PATTERNING OF LIPID BILAYERS USING UV LIGHT AND SELECTED USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-12-23 — — WO disclosed
US-20040180147-A1 Direct micro-patterning of lipid bilayers using UV light and selected uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-09-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230066723-A1 MICROPARTICLE COMPOSITIONS PHOSPHO1, SGMS2, CHMP4B S1PR1 287/4885S1PR3 168/4885S1PR4 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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