Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.32 |
| ▸ | PER2 | O15055 | 2/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | INMT | O95050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10130720 | 0.82 | AOC2 (0.37) | P2RX7GAAL3MBTL1 | |
| SCHEMBL7904697 | 0.75 | P2RX7 (0.39) | P2RX7GAA | |
| SCHEMBL9848826 | 0.71 | P2RX7 (0.39) | P2RX7GAAL3MBTL1 | |
| SCHEMBL25013635 | 0.70 | PIK3CD (0.44) | P2RX7PRMT5WDR77PER2CRY2 | |
| SCHEMBL18784060 | 0.69 | P2RX7 (0.41) | P2RX7GAA | |
| SCHEMBL10266064 | 0.69 | P2RX7 (0.38) | P2RX7GAA | |
| SCHEMBL20571751 | 0.69 | P2RX7 (0.51) | P2RX7PRMT5WDR77GAAL3MBTL1 | |
| SCHEMBL10130746 | 0.69 | PIK3CD (0.40) | GAAL3MBTL1 | |
| SCHEMBL9834992 | 0.69 | F2 (0.38) | P2RX7INMT | |
| SCHEMBL19546254 | 0.69 | F2 (0.38) | P2RX7INMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198288-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | VenatoRx Pharmaceuticals, Inc. | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198288-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | P2RX7 4582/4885PRMT5 495/4885WDR77 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.