Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593242 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBHPGDSIGMAR1 | |
| SCHEMBL18828589 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBHPGDSIGMAR1 | |
| SCHEMBL28139492 | 0.83 | KDM4E (0.51) | ALDH1A1MAPTPOLBHPGDSIGMAR1 | |
| SCHEMBL27666330 | 0.83 | CHRM1 (0.51) | KDM1AGBA1CHRM1CHRM3SLC6A2 | |
| SCHEMBL4321271 | 0.83 | CHRM1 (0.42) | KDM1AGBA1CHRM1CHRM3SIGMAR1 | |
| SCHEMBL4321273 | 0.83 | CHRM1 (0.42) | KDM1AGBA1CHRM1CHRM3SIGMAR1 | |
| SCHEMBL10784403 | 0.81 | KDM4E (0.54) | ALDH1A1MAPTPOLBHPGDSIGMAR1 | |
| SCHEMBL12735882 | 0.79 | SIGMAR1 (0.63) | KDM1AGBA1SIGMAR1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL31556504 | 0.78 | HTR2C (0.50) | CHRM1CHRM3SIGMAR1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL31556488 | 0.78 | HTR2C (0.50) | CHRM1CHRM3SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567685-B | High-wear-resistance solution polymerized styrene-butadiene rubber and preparation method thereof | 新疆独山子石油化工有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117567685-A | High-wear-resistance solution polymerized styrene-butadiene rubber and preparation method thereof | 新疆独山子石油化工有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20110263862-A1 | PIPERIDINE DERIVATIVE, PIPERAZINE DERIVATIVE AND AGENT FOR TREATMENT OF DISEASE INVOLVING CENTRAL NERVOUS SYSTEM DISORDERS | M'S SCIENCE CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| EP-2357171-A1 | PIPERIDINE DERIVATIVE, PIPERAZINE DERIVATIVE AND AGENT FOR TREATMENT OF DISEASE INVOLVING CENTRAL NERVOUS SYSTEM DISORDERS | M's Science Corporation (JP) | 2011-08-17 | — | — | EP | disclosed |
| US-20040044007-A1 | Indoline derivatives | H. LUNDBECK A/S (DK) | 2004-03-04 | — | — | US | disclosed |
| EP-1345921-A1 | 3-INDOLINE DERIVATIVES USEFUL IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGIC DISORDERS | H. Lundbeck A/S (DK) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051833-A1 | 3-INDOLINE DERIVATIVES USEFUL IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGIC DISORDERS | H. LUNDBECK A/S (DK) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044007-A1 | Indoline derivatives | CNR1, GRIN2C, HTR3C | KDM1A 902/4885GBA1 196/4885CHRM1 89/4885 |
| US-20110263862-A1 | PIPERIDINE DERIVATIVE, PIPERAZINE DERIVATIVE AND AGENT FOR TREATMENT OF DISEASE INVOLVING CENTRAL NERVOUS SYSTEM DISORDERS | SIGMAR1, OPRL1, OPRK1 | KDM1A 2961/4885GBA1 300/4885CHRM1 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.