Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609770 | 0.80 | CSNK2A2 (0.38) | CYP19A1KDM4EALDH1A1POLBPDE5A | |
| SCHEMBL23609484 | 0.73 | HPGDS (0.38) | CYP19A1KDM4EALDH1A1CTSLCTSS | |
| SCHEMBL23608952 | 0.71 | PDE5A (0.36) | KDM4EALDH1A1PDE5ACTSLCTSS | |
| SCHEMBL23609288 | 0.67 | S1PR1 (0.38) | ALDH1A1PDE5AS1PR1 | |
| SCHEMBL23609143 | 0.67 | SMN1; SMN2 (0.41) | CYP19A1KDM4EALDH1A1PDE5AKMT2A | |
| SCHEMBL23608891 | 0.66 | FPR3 (0.40) | CYP19A1KDM4EALDH1A1HPGDSKMT2A | |
| SCHEMBL23609168 | 0.65 | CYP19A1 (0.38) | CYP19A1KDM4EALDH1A1POLB | |
| SCHEMBL23608954 | 0.64 | CYP19A1 (0.51) | CYP19A1KMT2A | |
| SCHEMBL22414310 | 0.64 | POLB (0.62) | KDM4EALDH1A1POLBCTSLCTSS | |
| SCHEMBL1241605 | 0.63 | LIPC (0.46) | ALDH1A1KMT2AJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |