Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609770 | 0.90 | CSNK2A2 (0.38) | HPGDSGSK3BCSNK2A2FGFR2KDR | |
| SCHEMBL23608891 | 0.85 | FPR3 (0.40) | HPGDSGSK3BCSNK2A2FGFR2KDR | |
| SCHEMBL6965842 | 0.78 | CYP19A1 (0.54) | GSK3BCSNK2A2FGFR2KDRCSNK1A1 | |
| SCHEMBL23609248 | 0.77 | TLR8 (0.45) | GSK3BCSNK2A2FGFR2KDRCSNK1A1 | |
| SCHEMBL23875506 | 0.77 | MAPT (0.51) | GSK3BCSNK2A2FGFR2KDRCSNK1A1 | |
| SCHEMBL23608951 | 0.76 | CSNK2A2 (0.44) | GSK3BCSNK2A2FGFR2KDRCSNK1A1 | |
| SCHEMBL4621542 | 0.76 | NAMPT (0.46) | GSK3BNAMPT | |
| SCHEMBL23609170 | 0.73 | CYP19A1 (0.39) | HPGDSCYP19A1ALDH1A1CTSLCTSS | |
| SCHEMBL23609486 | 0.73 | LMNA (0.49) | GSK3BCSNK2A2FGFR2KDRCSNK1A1 | |
| SCHEMBL23130390 | 0.69 | KDM1A (0.51) | ALDH1A1NAMPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |