Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | STAT5B | P51692 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579126 | 1.00 | CYP19A1 (0.52) | CYP19A1ALDH1A1LMNASTAT5BPOLB | |
| SCHEMBL23579129 | 0.82 | STAT5B (0.43) | ALDH1A1STAT5BHTTAKT1MEN1 | |
| SCHEMBL31434459 | 0.82 | CRHBP (0.51) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5906827 | 0.79 | CHRM2 (0.50) | ALDH1A1HTTAKT1 | |
| SCHEMBL23609274 | 0.78 | NPC1 (0.40) | ALDH1A1STAT5BPOLBHTTAKT1 | |
| SCHEMBL23609281 | 0.78 | AR (0.38) | CYP19A1ALDH1A1STAT5BMAPTTHRB | |
| SCHEMBL29973211 | 0.78 | NPC1 (0.40) | ALDH1A1STAT5BPOLBHTTAKT1 | |
| SCHEMBL30270586 | 0.76 | CYP1A2 (0.52) | ALDH1A1LMNAPOLBMAPTKDM4E | |
| SCHEMBL13928897 | 0.76 | CYP1A2 (0.45) | ALDH1A1LMNAMAPTTHRBKDM4E | |
| SCHEMBL22897646 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTTHRBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |