Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MELK | Q14680 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406559 | 1.00 | RAB9A (0.55) | RAB9AALDH1A1MELKMAPTPOLB | |
| SCHEMBL29884265 | 0.93 | CYP1A2 (0.48) | RAB9AALDH1A1MELKPOLBKDM4E | |
| SCHEMBL23609495 | 0.93 | CYP1A2 (0.48) | RAB9AALDH1A1MELKPOLBKDM4E | |
| SCHEMBL16583870 | 0.84 | ALDH1A1 (0.53) | RAB9AALDH1A1MELKMAPTPOLB | |
| SCHEMBL23609177 | 0.81 | RAB9A (0.51) | RAB9AALDH1A1MAPTPOLBPKM | |
| SCHEMBL23579370 | 0.81 | MAPT (0.72) | RAB9AALDH1A1MAPTPOLBPKM | |
| SCHEMBL30406483 | 0.81 | RAB9A (0.51) | RAB9AALDH1A1MAPTPOLBPKM | |
| SCHEMBL15545810 | 0.80 | ALDH1A1 (0.49) | RAB9AALDH1A1MELKMAPTPOLB | |
| SCHEMBL2964824 | 0.79 | LMNA (0.62) | MAPTPOLBKDM4ELMNAALOX15 | |
| SCHEMBL23609322 | 0.78 | NR1H2 (0.37) | RAB9AALDH1A1MELKMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |