SCHEMBL2360950

SCHEMBL2360950

C=CC(=O)NN.NNC=O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
ALDH1A1 P00352 4/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
FGFR4 P22455 1/20 0.36
TGM2 P21980 4/20 0.32
LMNA P02545 3/20 0.32
CYP1A2 P05177 1/20 0.32
NFKB1 P19838 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
THPO P40225 1/20 0.32
F13A1 P00488 1/20 0.30
TGM1 P22735 1/20 0.30
TGM3 Q08188 1/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168192 0.89
Hydrochloric Acid SCHEMBL27812565 0.86
Water SCHEMBL28045867 0.86
Bromide SCHEMBL28449390 0.86
Hydrochloric Acid SCHEMBL11660494 0.86
Acrylic Acid SCHEMBL9953445 0.81 LMNA (0.56) TSHRALDH1A1MAPK1TDP1FGFR4
Acrylamide SCHEMBL27937634 0.81 TSHR (0.61) TSHRALDH1A1MAPK1TDP1FGFR4
Oxalic Acid SCHEMBL10889014 0.79 TSHR (0.40) TSHRALDH1A1MAPK1TDP1FGFR4
Acrylamide SCHEMBL8606934 0.78
Glutaral SCHEMBL10558842 0.77 HIF1A (0.43) TSHRALDH1A1MAPK1TDP1FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116925507-A Heat-resistant thermoplastic polyester composition and preparation method thereof 江苏康辉新材料科技有限公司 2023-10-24 CN claimed
CN-116925508-A Heat-resistant degradable polyester composition and preparation method thereof 江苏康辉新材料科技有限公司 2023-10-24 CN claimed
CN-116904005-A Polylactic acid nucleating agent, heat-resistant polylactic acid composition and preparation method thereof 大连理工大学 2023-10-20 CN claimed
CN-116694052-A Furanyl polyester composition with high crystallization property and preparation method thereof 大连理工大学 2023-09-05 CN claimed
CN-116640428-A Polyester nucleating agent and preparation method thereof 大连理工大学 2023-08-25 CN claimed
EP-4146744-A1 HETERO-FUNCTIONAL COATING FOR CONJUGATING BIOMOLECULES ON A SOLID SUPPORT AND USE THEREOF FOR BIOANALYSIS Waters Technologies Corporation (US) 2023-03-15 EP claimed
CN-115551956-A Heterofunctional coating for conjugating biomolecules on solid supports and use thereof for bioanalysis 沃特世科技公司 2022-12-30 CN claimed
CN-115353647-A Self-repairing marine-source collagen peptide-based composite hydrogel and preparation method thereof 中国石油大学(华东) 2022-11-18 CN claimed
WO-2021224887-A1 HETERO-FUNCTIONAL COATING FOR CONJUGATING BIOMOLECULES ON A SOLID SUPPORT AND USE THEREOF FOR BIOANALYSIS WATERS TECHNOLOGIES CORPORATION (US) 2021-11-11 WO claimed
EP-1590373-B1 CONJUGATES OBTAINED BY REDUCTIVE AMINATION OF SEROTYPE 5 PNEUMOCOCCUS CAPSULAR POLYSACCHARIDE SANOFI PASTEUR (FR) 2011-08-17 EP claimed
EP-1590373-A1 CONJUGATES OBTAINED BY REDUCTIVE AMINATION OF SEROTYPE 5 PNEUMOCOCCUS CAPSULAR POLYSACCHARIDE Sanofi Pasteur (FR) 2005-11-02 EP claimed
US-20040170638-A1 Conjugates obtained by reductive amination of the pneumococcus serotype 5 capsular polysaccharide AVENTIS PASTEUR, S.A. 2004-09-02 US claimed
WO-2004067574-A1 CONJUGATES OBTAINED BY REDUCTIVE AMINATION OF SEROTYPE 5 PNEUMOCOCCUS CAPSULAR POLYSACCHARIDE SANOFI PASTEUR (FR) 2004-08-12 WO claimed
EP-1363672-A1 CARRIER SYSTEMS COMPRISING VITAMIN B12 - BIODEGRADABLE MICRO PARTICULATE CONJU GATES FOR PERORAL DELIVERY OF DRUGS, PEPTIDES/PROTEINS AND VACCINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; An Indian Registered Body Incorporated Under The Registration of Societies Act; (IN) 2003-11-26 EP claimed
US-20020192235-A1 NOVEL VITAMIN B12 - BIODEGRADABLE MICRO PARTICULATE CONJUGATE CARRIER SYSTEMS FOR PERORAL DELIVERY OF DRUGS, THERAPEUTIC PEPTIDES/PROTEINS AND VACCINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2002-12-19 US claimed
US-6482413-B1 Vitamin B12 —biodegradable micro particulate conjugate carrier systems for peroral delivery of drugs, therapeutic peptides/proteins and vaccines COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-11-19 US claimed
WO-2002067995-A1 CARRIER SYSTEMS COMPRISING VITAMIN B12 - BIODEGRADABLE MICRO PARTICULATE CONJU GATES FOR PERORAL DELIVERY OF DRUGS, PEPTIDES/PROTEINS AND VACCINES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-09-06 WO claimed
EP-0491501-B1 The use of hydrazide stabilizers for 3-isothiazolones ROHM & HAAS (US) 1996-07-10 EP claimed
EP-0491501-A1 The use of hydrazide stabilizers for 3-isothiazolones ROHM AND HAAS COMPANY (US) 1992-06-24 EP claimed
US-5118699-A Microbiocides ROHM AND HAAS COMPANY (US) 1992-06-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040170638-A1 Conjugates obtained by reductive amination of the pneumococcus serotype 5 capsular polysaccharide FUT5, B3GNT2, CSGALNACT1 TSHR 3909/4885ALDH1A1 2038/4885MAPK1 3563/4885
US-20020192235-A1 NOVEL VITAMIN B12 - BIODEGRADABLE MICRO PARTICULATE CONJUGATE CARRIER SYSTEMS FOR PERORAL DELIVERY OF DRUGS, THERAPEUTIC PEPTIDES/PROTEINS AND VACCINES FOLR2, MMAB, VNN1 TSHR 219/4885ALDH1A1 4813/4885MAPK1 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.