Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330120 | 0.91 | LMNA (0.39) | LMNA | |
| SCHEMBL5919388 | 0.88 | LMNA (0.44) | LMNA | |
| SCHEMBL516767 | 0.88 | LMNA (0.44) | LMNA | |
| SCHEMBL330134 | 0.88 | LMNA (0.44) | LMNA | |
| SCHEMBL4850734 | 0.88 | LMNA (0.44) | LMNA | |
| SCHEMBL3833781 | 0.88 | LMNA (0.44) | LMNA | |
| SCHEMBL4826115 | 0.88 | LMNA (0.44) | LMNA | |
| Fluoride SCHEMBL616101 | 0.84 | LMNA (0.42) | LMNA | |
| SCHEMBL24867 | 0.78 | — | — | |
| Fluoride SCHEMBL8732474 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 977 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547665-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-07-04 | — | — | EP | claimed |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-02-02 | — | — | US | claimed |
| US-9499524-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-22 | — | — | US | claimed |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2016-10-20 | — | — | US | claimed |
| EP-2688864-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-01-29 | — | — | EP | claimed |
| US-20140005235-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-02 | — | — | US | claimed |
| EP-2427427-B1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2013-12-25 | — | — | EP | claimed |
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | claimed |
| EP-2547665-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-01-23 | — | — | EP | claimed |
| US-20130012547-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-10 | — | — | US | claimed |
| US-20030055031-A1 | Methods of using thiazolobenzoheterocycles | RHONE-POULENC RORER S.A. | 2003-03-20 | — | — | US | claimed |
| US-6448241-B1 | THESE COMPOUNDS ARE ANTICONVULSANTS AND INTERFERE WITH GLUTAMATERGIC TRANSMISSION AND ARE THEREFORE USEFUL FOR THE TREATMENT OR PREVENTION OF ALL ISCHAEMIAS FOLLOWING CEREBROVASCULAR ACCIDENTS | AVENTIS PHARMA S.A. (FR) | 2002-09-10 | — | — | US | claimed |
| EP-0966473-B1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-07-24 | — | — | EP | claimed |
| US-6423715-B1 | ANTICONVULSANTS | AVENTIS PHARMA S.A. (FR) | 2002-07-23 | — | — | US | claimed |
| US-6288075-B1 | ANTIEPILEPTIC AGENTS; NERVOUS SYSTEM, BRAIN, AND CARDIOVASCULAR DISORDERS | RHONE-POULENC RORER S.A. (FR) | 2001-09-11 | — | — | US | claimed |
| EP-0966473-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | Aventis Pharma S.A. (FR) | 1999-12-29 | — | — | EP | claimed |
| WO-1998038194-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1998-09-03 | — | — | WO | claimed |
| EP-0234045-B1 | A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | claimed |
| US-4843068-A | INSECTICIDES, MITICIDES, FUNGICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | claimed |
| EP-0234045-A2 | A pyrazole oxime derivative and its production and use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005235-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | LMNA 1569/4885 |
| US-20030055031-A1 | Methods of using thiazolobenzoheterocycles | SLCO2B1, SLCO1B1, CYP21A2 | LMNA 2635/4885 |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | LMNA 2062/4885 |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | LMNA 2062/4885 |
| US-20130012547-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CYP51A1 | LMNA 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.