SCHEMBL330134

SCHEMBL330134

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)[S]

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850734 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL4826115 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL516767 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL5919388 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL3833781 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
Fluoride SCHEMBL616101 0.96 LMNA (0.42) LMNATHRBCA2
SCHEMBL330120 0.96 LMNA (0.39) LMNATHRB
SCHEMBL236099 0.88 LMNA (0.35) LMNA
SCHEMBL1707474 0.78 LMNA (0.61) LMNATHRBCA2CA1MMP1
Perflexane SCHEMBL3671912 0.78 LMNA (0.61) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024101172-A1 (HETERO)ARYL UREA COMPOUND AND INSECTICIDE 日本曹達株式会社 2024-05-16 WO disclosed
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2023-11-23 US disclosed
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2021-07-29 US disclosed
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2021-05-04 US disclosed
EP-3059235-B1 TETRAZOLINONE DERIVATIVES AND THEIR USE FOR CONTROLLING PESTS SUMITOMO CHEMICAL CO (JP) 2020-10-28 EP disclosed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
EP-3040332-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-06-03 EP disclosed
EP-2990404-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-05-27 EP disclosed
EP-0844243-B1 Sulfonamide compound and method for its production, metal chelate compound employing the sulfonamide compound, and optical recording medium employing the metal chelate compound MITSUBISHI CHEM CORP (JP) 2004-08-25 EP disclosed
EP-1209166-B1 NOVEL A-500359 DERIVATIVES SANKYO CO (JP) 2004-03-31 EP disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed
US-20030171330-A1 Antibacterial compound SANKYO COMPANY, LIMITED (JP) 2003-09-11 US disclosed
EP-1275517-A1 OPTICAL RECORDING MEDIUM MITSUBISHI CHEMICAL CORPORATION (JP) 2003-01-15 EP disclosed
EP-1209166-A1 NOVEL A-500359 DERIVATIVES Sankyo Company, Limited (JP) 2002-05-29 EP disclosed
US-20020051941-A1 Optical recording medium MITSUBISHI CHEMICAL CORPORATION (JP) 2002-05-02 US disclosed
US-6284877-B1 Sulfonamide compound and method for its production, metal chelate compound employing the sulfonamide compound, and optical recording medium employing the metal chelate compound MITSUBISHI CHEMICAL CORPORATION (JP) 2001-09-04 US disclosed
US-6225023-B1 INTERMEDIATE USEFUL FOR THE SYNTHESIS OF AZO DYE, DESIGNED TO USE SEMICONDUCTOR LASER OF SHORT WAVELENGTH. MITSUBISHI CHEMICAL CORPORATION (JP) 2001-05-01 US disclosed
EP-0844243-A1 Sulfonamide compound and method for its production, metal chelate compound employing the sulfonamide compound, and optical recording medium employing the metal chelate compound MITSUBISHI CHEMICAL CORPORATION (JP) 1998-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171330-A1 Antibacterial compound TLR1, MPO, O60361 LMNA 4477/4885THRB 3349/4885CA2 1863/4885
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 LMNA 3120/4885THRB 2069/4885CA2 3970/4885
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 LMNA 3120/4885THRB 2069/4885CA2 3970/4885
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 LMNA 3120/4885THRB 2069/4885CA2 3970/4885
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 LMNA 3120/4885THRB 2069/4885CA2 3970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.