Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714440 | 0.89 | KDM1A (0.51) | KDM1AKDM1BTHRBDPP4NPSR1 | |
| SCHEMBL22777936 | 0.89 | KDM1A (0.51) | KDM1AKDM1BTHRBDPP4NPSR1 | |
| SCHEMBL30021045 | 0.89 | KDM1A (0.56) | KDM1AKDM1BMEN1LMNAKMT2A | |
| SCHEMBL22778088 | 0.89 | KDM1A (0.56) | KDM1AKDM1BMEN1LMNAKMT2A | |
| SCHEMBL23612201 | 0.76 | LMNA (0.39) | KDM1AKDM1BMEN1LMNAKMT2A | |
| SCHEMBL29739167 | 0.71 | KDM1A (0.58) | KDM1AKDM1BDPP4DGAT1 | |
| SCHEMBL8243578 | 0.71 | KDM1A (0.58) | KDM1AKDM1BDPP4DGAT1 | |
| SCHEMBL20177600 | 0.70 | MTNR1A (0.48) | KDM1AKDM1BMEN1LMNAKMT2A | |
| SCHEMBL22778039 | 0.69 | CHRNB2 (0.37) | KDM1AKDM1BLMNA | |
| SCHEMBL17997271 | 0.69 | KDM1A (0.55) | KDM1AKDM1BMEN1KMT2ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085061-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021138419-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC, (US) | 2021-07-08 | — | — | WO | disclosed |
| WO-2021138434-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-07-08 | — | — | WO | disclosed |