Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.66 |
| ▸ | HTR1B | P28222 | 5/20 | 0.63 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20436335 | 0.81 | HTR2A (0.63) | HTR1DHTR1BMPOSLC6A4NR3C1 | |
| SCHEMBL22643951 | 0.81 | HTR1D (0.75) | HTR1DHTR1BMPOHTR2AHTR1A | |
| SCHEMBL25903380 | 0.81 | HTR1D (0.69) | HTR1DHTR1BSPRHTR2ATP53 | |
| SCHEMBL1272247 | 0.80 | MPO (0.64) | MPOSLC6A4HTR2AHTR1A | |
| SCHEMBL2540516 | 0.80 | HTR1D (1.00) | HTR1DHTR1BMPOHTR6HTR7 | |
| SCHEMBL7755853 | 0.80 | HTR1D (0.73) | HTR1DHTR1BMPOSLC6A4SPR | |
| Hydrochloric Acid SCHEMBL7816441 | 0.78 | HTR1D (0.97) | HTR1DHTR1BMPOHTR6HTR7 | |
| SCHEMBL1272559 | 0.76 | HTR2A (0.57) | HTR1DHTR1BMPOSLC6A4HTR6 | |
| SCHEMBL22643883 | 0.76 | HTR1D (0.68) | HTR1DHTR1BSLC6A4NR3C1PGR | |
| Oxalic Acid SCHEMBL2535942 | 0.76 | HTR1D (0.84) | HTR1DHTR1BMPOHTR6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11052092-B2 | N-{[2-(piperidin-1-yl)phenyl](phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating autoimmune diseases | GENFIT (FR) | 2021-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11052092-B2 | N-{[2-(piperidin-1-yl)phenyl](phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating autoimmune diseases | RORA, RORC, RORB | HTR1D 2935/4885HTR1B 3821/4885MPO 3422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.