SCHEMBL23612581

SCHEMBL23612581

NC(=O)C1=CC=CC2Nc3ccccc3N=C12

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 2/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19999997 0.64 RAB9A (0.36) MAPTALDH1A1LMNAKDM4EMEN1
SCHEMBL24650725 0.62 MAPT (0.50) MAPTALDH1A1LMNAKDM4EMEN1
SCHEMBL4098083 0.59 HTR2B (0.31)
SCHEMBL1036164 0.59 MAPT (0.38) MAPTALDH1A1LMNAKDM4EMEN1
SCHEMBL31319868 0.58 NOS3 (0.34) MAPTALDH1A1LMNAKDM4EMEN1
SCHEMBL35211808 0.58 CES2 (0.33) MAPTALDH1A1LMNAGAARAB9A
SCHEMBL5727673 0.58 NOS3 (0.34) MAPTALDH1A1LMNAKDM4EMEN1
SCHEMBL6898456 0.58 CES2 (0.33) MAPTALDH1A1LMNAGAARAB9A
SCHEMBL5891203 0.57 TTK (0.36) LMNA
SCHEMBL24202464 0.56 RAB9A (0.44) MAPTALDH1A1LMNAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053205-B2 Phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11053205-B2 Phenazine derivatives as antimicrobial agents ROS1, NOX4, PRDX3 MAPT 2601/4885ALDH1A1 701/4885LMNA 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.