Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534916 | 0.81 | KMT2A (0.61) | GAAMETKMT2AMEN1ALDH1A1 | |
| SCHEMBL25350141 | 0.75 | LMNA (0.51) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4727160 | 0.75 | HTT (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31024013 | 0.74 | TP53 (0.59) | KMT2AALDH1A1CA1CA2 | |
| SCHEMBL12643250 | 0.73 | TSHR (0.70) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10801011 | 0.73 | LMNA (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2360974 | 0.71 | ALDH1A1 (0.84) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4728733 | 0.71 | TP53 (0.63) | METKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL370668 | 0.70 | KMT2A (0.70) | GAAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4158554 | 0.70 | KMT2A (0.70) | GAAKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486191-B2 | FUNGICIDAL ACTIVITY | BAYER AG (DE) | 2002-11-26 | — | — | US | claimed |
| US-20020094936-A1 | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | ASSMANN LUTZ (DE) | 2002-07-18 | — | — | US | claimed |
| US-6350770-B1 | MICROBIOCIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-26 | — | — | US | claimed |
| US-20020022728-A1 | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | ASSMANN LUTZ (DE) | 2002-02-21 | — | — | US | claimed |
| US-6262100-B1 | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | claimed |
| CN-1264367-A | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | BAYER AG (DE) | 2000-08-23 | — | — | CN | claimed |
| EP-1003726-A1 | NITROPHENYL-SULFONYL-IMIDAZOLES AND USE THEREOF FOR CONTROLLING VEGETABLE AND ANIMAL PESTS | Bayer Aktiengesellschaft (DE) | 2000-05-31 | — | — | EP | claimed |
| WO-1999005116-A1 | NITROPHENYL-SULFONYL-IMIDAZOLES AND USE THEREOF FOR CONTROLLING VEGETABLE AND ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | claimed |
| EP-2201001-B1 | NOVEL IMIDAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-14 | — | — | EP | disclosed |
| EP-2201000-B1 | NOVEL IMIDAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-31 | — | — | EP | disclosed |
| US-6486191-B2 | FUNGICIDAL ACTIVITY | BAYER AG (DE) | 2002-11-26 | — | — | US | disclosed |
| US-6486191-B2 | FUNGICIDAL ACTIVITY | BAYER AG (DE) | 2002-11-26 | — | — | US | disclosed |
| US-6486191-B2 | FUNGICIDAL ACTIVITY | BAYER AG (DE) | 2002-11-26 | — | — | US | disclosed |
| US-20020094936-A1 | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | ASSMANN LUTZ (DE) | 2002-07-18 | — | — | US | disclosed |
| CN-1264367-A | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | BAYER AG (DE) | 2000-08-23 | — | — | CN | disclosed |
| CN-1264367-A | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | BAYER AG (DE) | 2000-08-23 | — | — | CN | disclosed |
| EP-1003726-A1 | NITROPHENYL-SULFONYL-IMIDAZOLES AND USE THEREOF FOR CONTROLLING VEGETABLE AND ANIMAL PESTS | Bayer Aktiengesellschaft (DE) | 2000-05-31 | — | — | EP | disclosed |
| EP-1003726-A1 | NITROPHENYL-SULFONYL-IMIDAZOLES AND USE THEREOF FOR CONTROLLING VEGETABLE AND ANIMAL PESTS | Bayer Aktiengesellschaft (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999005116-A1 | NITROPHENYL-SULFONYL-IMIDAZOLES AND USE THEREOF FOR CONTROLLING VEGETABLE AND ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |
| WO-1999005116-A1 | NITROPHENYL-SULFONYL-IMIDAZOLES AND USE THEREOF FOR CONTROLLING VEGETABLE AND ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022728-A1 | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | NOD1, NMRAL1, NAT1 | GAA 798/4885MET 4285/4885KMT2A 1335/4885 |
| US-20020094936-A1 | Nitrophenyl-sulfonyl-imidazoles and use thereof for controlling vegetable and animal pests | NOD1, NMRAL1, NAT1 | GAA 798/4885MET 4285/4885KMT2A 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.