Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616953 | 0.81 | CFD (0.57) | CFDSUCNR1 | |
| SCHEMBL21439726 | 0.75 | PKM (0.43) | CFDSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL21438387 | 0.75 | CFD (0.44) | CFDSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL21439705 | 0.75 | NLRP3 (0.43) | CFDSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL21439704 | 0.74 | PKM (0.45) | CFDSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL21438818 | 0.74 | CFD (0.49) | CFDSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL15183757 | 0.74 | KDM4E (0.53) | LMNAALDH1A1TSHRNPSR1HSD17B10 | |
| SCHEMBL21439744 | 0.74 | TSHR (0.42) | CFDSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL21439637 | 0.73 | POLB (0.40) | CFDSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL23217837 | 0.72 | ALDH1A1 (0.39) | CFDSMN1; SMN2LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |