Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168302 | 0.78 | PDCD1 (0.51) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL4746034 | 0.76 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL17557730 | 0.76 | CA12 (0.41) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5545353 | 0.74 | ALDH1A1 (0.60) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL10376521 | 0.74 | SNCA (0.52) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL2345447 | 0.72 | ALDH1A1 (0.60) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL5531110 | 0.71 | HPGD (0.67) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL21577940 | 0.70 | CYP4F2 (0.39) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL16087758 | 0.70 | TSHR (0.46) | HSD17B10ALDH1A1LMNACA12CA1 | |
| SCHEMBL6934601 | 0.69 | ALDH1A1 (0.62) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136390-A1 | BLOOD COAGULATION FACTOR XIA INHIBITOR | 上海京新生物医药有限公司 | 2021-07-08 | — | — | WO | disclosed |