Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360806 | 0.85 | CSNK1D (0.51) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10380499 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL2362261 | 0.82 | CHRNA7 (0.45) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28837680 | 0.76 | POLB (0.56) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9032997 | 0.76 | ALDH1A1 (0.62) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL3337505 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL3335014 | 0.74 | ALDH1A1 (0.61) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL20982568 | 0.74 | MMP2 (0.57) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2893147 | 0.74 | MEN1 (0.60) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7450235 | 0.74 | KDM4E (0.55) | POLBMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |