SCHEMBL23620172

SCHEMBL23620172

O=S(=O)(Cl)c1cc(Br)cc2cnc(Cl)cc12

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.35
EGFR P00533 1/20 0.33
ALPL P05186 1/20 0.31
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23620171 0.86 CSNK2A1 (0.37) CSNK2A1EGFRALPLCHRM1
SCHEMBL30812900 0.78 CSNK2A1 (0.35) CSNK2A1CHRM1
SCHEMBL23620170 0.76 LMNA (0.34)
SCHEMBL5009195 0.74 PRKACA (0.37)
SCHEMBL31456336 0.72 TRPV4 (0.31)
SCHEMBL24713533 0.70 CSNK2A1 (0.31) CSNK2A1EGFR
SCHEMBL23619972 0.70 CSNK2A1 (0.31) CSNK2A1EGFR
SCHEMBL789628 0.68 ALPL (0.47) ALPL
SCHEMBL23619727 0.68 LMNA (0.37) EGFRALPL
SCHEMBL23140985 0.67 TRPV4 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4079724-B1 2-(2-CHLOROPHENYL)-N-(5-SULFAMOYLISOQUINOLIN-7-YL)ACETAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS P2X4 ANTAGONISTS FOR THE TREATMENT OF E.G. URINARY TRACT DISEASES WUHAN LL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD (CN) 2025-11-12 EP disclosed
CN-114901642-B Fused ring compound and application thereof 武汉朗来科技发展有限公司 2024-02-23 CN disclosed
US-20230118751-A1 FUSED RING COMPOUND AND APPLICATION THEREOF WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2023-04-20 US disclosed
US-20230118751-A1 FUSED RING COMPOUND AND APPLICATION THEREOF WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2023-04-20 US disclosed
EP-4079724-A1 FUSED RING COMPOUND AND APPLICATION THEREOF Wuhan LL Science and Technology Development Co., Ltd. (CN) 2022-10-26 EP disclosed
EP-4079724-A1 FUSED RING COMPOUND AND APPLICATION THEREOF Wuhan LL Science and Technology Development Co., Ltd. (CN) 2022-10-26 EP disclosed
CN-114901642-A Fused ring compound and application thereof 武汉朗来科技发展有限公司 2022-08-12 CN disclosed
WO-2021136238-A1 FUSED RING COMPOUND AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2021-07-08 WO disclosed
WO-2021136238-A1 FUSED RING COMPOUND AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2021-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230118751-A1 FUSED RING COMPOUND AND APPLICATION THEREOF P2RX4, P2RX3, P2RX2 CSNK2A1 2972/4885EGFR 4473/4885ALPL 1035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.