Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361026 | 0.94 | DGAT1 (0.41) | PTGER4DGAT1PTGESMAOAMAOB | |
| SCHEMBL2361142 | 0.84 | DGAT1 (0.44) | DGAT1PTGESNPC1RAB9AMAPT | |
| SCHEMBL2364793 | 0.79 | EHMT2 (0.45) | PTGER4MAPT | |
| SCHEMBL2365383 | 0.77 | PTGES (0.46) | DGAT1PTGESNPC1RAB9ANR2E3 | |
| SCHEMBL2360771 | 0.77 | PTGES (0.50) | DGAT1PTGESNPC1ALDH1A1RAB9A | |
| SCHEMBL2361289 | 0.77 | DGAT1 (0.48) | DGAT1PTGESMAOBMAPTNR2E3 | |
| SCHEMBL2361453 | 0.74 | DGAT1 (0.46) | DGAT1PTGESMAOBALDH1A1MAPT | |
| SCHEMBL2362023 | 0.74 | RHEB (0.57) | DGAT1PTGESNPC1ALDH1A1RAB9A | |
| SCHEMBL2362016 | 0.73 | EHMT2 (0.48) | PTGER4PTGESMAPT | |
| SCHEMBL2361492 | 0.73 | NR2E3 (0.64) | DGAT1NPC1RAB9AMAPTNR2E3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | claimed |